Search results for "Intestinal microbiology"

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Shifts in gut microbiota composition in an APP/PSS1 transgenic mouse model of Alzheimer's disease during lifespan.

2017

Alzheimer's disease (AD) is the most common form of dementia and one of the major causes of disability and dependency in older people. Accumulating evidences link gut microbiota with different diseases and its relationship with neurodegenerative diseases is becoming most intriguing. This study was aimed to compare the gut microbiota of transgenic APP/PS1 (TG) mice, a well‐established deterministic mouse model of AD, with their C57BL/6 wild‐type (WT) littermates. Faecal samples were collected from 3‐, 6‐ and 24‐month‐old mice and analysed by pyrosequencing of the V1–V3 region of the bacterial 16S rRNA genes. Bacterial profiles were similar in all young mice (3 months old), and started to div…

0301 basic medicineGenetically modified mouseMaleAgingRikenellaceaeTransgeneFirmicutesMice TransgenicDiseaseGut floraApplied Microbiology and Biotechnology03 medical and health sciencesMiceAlzheimer DiseaseRNA Ribosomal 16SProteobacteriamedicineDementiaIndicatorsAnimalsHumansNeuroinflammationMarkersbiologyIntestinal microbiologyBacteroidetesbiology.organism_classificationmedicine.diseaseGastrointestinal MicrobiomeMice Inbred C57BLDisease Models Animal030104 developmental biologyAgeingImmunologyMicrobial structureDisease processesLetters in applied microbiology
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Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metab…

2021

Gut: first published.

Male0301 basic medicine2312MicrobiologiaGut floraTranscriptomeMice0302 clinical medicineOverweight persons1506Gut MicrobiotaPrefrontal cortexhealth care economics and organizationsdigestive oral and skin physiologyGastroenterologyIntestins -- MalaltiesFecal Microbiota TransplantationMiddle AgedPersones obesesserotonin3. Good healthInhibition PsychologicalIntestins -- MicrobiologiaPhenotypemedicine.anatomical_structureintestinal microbiology ; microbiota ; obesity.ObesitatFemaleIntestines -- DiseasesdopamineperformanceAdultmedicine.medical_specialtytryptophan depletionPhysical exerciseBiologyIntestines -- Microbiologydigestive systemMicrobiologyAmino Acids Aromatic03 medical and health sciencesMetabolomicsInternal medicinemedicineAnimalsHumansObesityAnterior cingulate cortexAgedIntestinal microbiologyMetabolismbiology.organism_classificationCarbonGastrointestinal MicrobiomeFatty LiverCross-Sectional Studies030104 developmental biologyEndocrinologyTranscriptome030217 neurology & neurosurgeryStroop effect
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